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Phosphonate and phosphinate metabolism

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
CTP + [2-(trimethylamino)ethyl]phosphonate <=> diphosphate + CMP-N-trimethyl-2-aminoethylphosphonate 2.7.7.15 choline-phosphate cytidylyltransferase
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N-Dimethyl-2-aminoethylphosphonate + Activated_methyl_group <=> [2-(trimethylamino)ethyl]phosphonate not assigned
 –
H2O + phosphonoacetaldehyde <=> H+ + phosphate + acetaldehyde 3.11.1.1 phosphonoacetaldehyde hydrolase
–
Phosphonopyruvate + L-glutamate <=> phosphonoalanine + 2-oxoglutarate 2.6.1
–
2-amino-1-hydroxyethylphosphonate + O2 <=> glycine + phosphate 1.13.11.78 2-amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming)
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hydroxymethylphosphonate + O2 <=> formate + phosphate + H+ 1.13.11.72 2-hydroxyethylphosphonate dioxygenase
1.13.11.89 (hydroxymethyl)phosphonate dioxygenase
–
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methylphosphonate + ATP <=> alpha-D-ribose_1-methylphosphonate_5-triphosphate + adenine 2.7.8.37 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase
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H+ + phosphoenolpyruvate <=> Phosphonopyruvate 5.4.2.9 phosphoenolpyruvate mutase
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pyruvate + 2-aminoethylphosphonate <=> L-alanine + phosphonoacetaldehyde 2.6.1.18 beta-alanine---pyruvate transaminase
2.6.1.37 2-aminoethylphosphonate---pyruvate transaminase
–
–
CMP-5'-phosphonoformate + 3-phospho-D-glycerate <=> 1-carboxyvinyl_carboxyphosphonate + CMP + phosphate not assigned
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phosphonoacetaldehyde <=> L-Arg-L-2-amino-5-phosphono-3-cis-pentenoate not assigned
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phosphonoacetaldehyde <=> Rhizocticin_B not assigned
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CMP-2-aminoethylphosphonate + ceramide <=> Ceramide_2-aminoethylphosphonate + CMP 2.7.8
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2-aminoethylphosphonate + 2-oxoglutarate + O2 <=> 2-amino-1-hydroxyethylphosphonate + succinate + CO2 1.14.11.46 2-aminoethylphosphonate dioxygenase
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L-glutamyl_gamma-phosphinic_acid + acetyl-CoA <=> H+ + N-acetyldemethylphosphinothricin + CoA 2.3.1.183 phosphinothricin acetyltransferase
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2-Oxophosphonobutanoate <=> FR-900098 not assigned
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methylphosphonate + O2 + 2-oxoglutarate <=> hydroxymethylphosphonate + succinate + CO2 1.14.11.71 methylphosphonate hydroxylase
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phosphonoacetaldehyde <=> Rhizocticin_C not assigned
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3-(hydroxyphosphonoylmethyl)malate <=> Deamino-alpha-keto-demethylphosphinothricin not assigned
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H2O + Phosphonoacetate <=> H+ + phosphate + acetate 3.11.1.2 phosphonoacetate hydrolase
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Phosphinothricin + acetyl-CoA <=> H+ + CoA + N-acetylphosphinothricin 2.3.1.183 phosphinothricin acetyltransferase
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2-hydroxyethylphosphonate + O2 <=> H+ + hydroxymethylphosphonate + formate 1.13.11.72 2-hydroxyethylphosphonate dioxygenase
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N-acetyldemethylphosphinothricin + 2 L-alanine + 3 ATP + H2O <=> N-acetyldemethyl_phosphinothricin_tripeptide + 3 AMP + 3 diphosphate not assigned
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2-amino-1-hydroxyethylphosphonate <=> Lipophosphonoglycan not assigned
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alpha-D-ribose_1-methylphosphonate_5-triphosphate + H2O <=> alpha-D-ribose_1-methylphosphonate_5-phosphate + diphosphate + H+ 3.6.1.63 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase
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1-carboxyvinyl_carboxyphosphonate + H+ <=> CO2 + (hydroxyphosphinyl)pyruvate 2.7.8.23 carboxyvinyl-carboxyphosphonate phosphorylmutase
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Phosphonoformate + CTP <=> CMP-5''-phosphonoformate + diphosphate 2.7.7.93 phosphonoformate cytidylyltransferase
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2-aminoethylphosphonate <=> Ciliatocholate not assigned
 –
L-N-acetylphosphinothricin_bialophos + H2O <=> phosphinotricyl-alanyl-alanine/out + acetate 3.1.1
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N-acetyldemethylphosphinothricin + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> N-acetylphosphinothricin + Cobalamin + 5''-Deoxyadenosine + L-methionine 2.1.1.326 N-acetyldemethylphosphinothricin P-methyltransferase
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phosphonoacetaldehyde + NADPH + H+ <=> 2-hydroxyethylphosphonate + NADP+ 1.1.1.309 phosphonoacetaldehyde reductase (NADH)
1.1.99.B6
–
–
Diacylglyceryl-2-aminoethylphosphonate <=> Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate not assigned
 –
H2O + D-ribofuranose_2,5-bisphosphate <=> D-ribose_5-phosphate + phosphate 3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase
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CTP + 2-aminoethylphosphonate <=> CMP-2-aminoethylphosphonate + diphosphate 2.7.7.14 ethanolamine-phosphate cytidylyltransferase
2.7.7.an
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CMP-2-aminoethylphosphonate + diacylglycerol <=> CMP + Diacylglyceryl-2-aminoethylphosphonate 2.7.8.1 ethanolaminephosphotransferase
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N-acetyldemethyl_phosphinothricin_tripeptide + methylcobalamin + S-adenosyl-L-methionine + H+ + e- <=> L-N-acetylphosphinothricin_bialophos + Cobalamin + 5''-Deoxyadenosine + L-methionine 2.1.1.326 N-acetyldemethylphosphinothricin P-methyltransferase
–
Deamino-alpha-keto-demethylphosphinothricin <=> L-glutamyl_gamma-phosphinic_acid not assigned
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2-Acetamidoethylphosphonate <=> N-Ethylacetamide not assigned
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5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + H2O <=> H+ + alpha-D-ribose_1,5-bisphosphate 3.1.4.55 phosphoribosyl 1,2-cyclic phosphate phosphodiesterase
–
N-Monomethyl-2-aminoethylphosphonate <=> N-Dimethyl-2-aminoethylphosphonate not assigned
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phosphonoacetaldehyde + NAD+ + H2O <=> Phosphonoacetate + NADH + H+ 1.2.1
1.2.1.3 aldehyde dehydrogenase (NAD+)
–
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2-hydroxyethylphosphonate + O2 <=> methylphosphonate + HCO3- + H+ 1.13.11.73 methylphosphonate synthase
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Formylphosphonate <=> Phosphonoformate not assigned
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phosphinotricyl-alanyl-alanine/out <=> Phosphinothricin not assigned
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2-aminoethylphosphonate <=> N-Monomethyl-2-aminoethylphosphonate not assigned
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Phosphonopyruvate + acetyl-CoA + H2O <=> (R)-2-(phosphonomethyl)malate + CoA + H+ 2.3.3.19 2-phosphonomethylmalate synthase
–
2-hydroxyethylphosphonate + NAD+ <=> phosphonoacetaldehyde + NADH + H+ 1.1.1.309 phosphonoacetaldehyde reductase (NADH)
–
Phosphonopyruvate + H2O <=> H+ + pyruvate + phosphate 3.11.1.3 phosphonopyruvate hydrolase
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N-acetylphosphinothricin + H2O <=> Phosphinothricin + acetate not assigned
 –
2-(hydroxyphosphonoylmethyl)malate <=> 3-(hydroxyphosphonoylmethyl)malate 4.2.1.166 phosphinomethylmalate isomerase
–
5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + H2O <=> D-ribofuranose_2,5-bisphosphate + H+ 3.1.4.57 phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase
–
CMP-N-trimethyl-2-aminoethylphosphonate + diacylglycerol <=> CMP + Diacylglyceryl-N-trimethyl-2-aminoethylphosphonate 2.7.8.2 diacylglycerol cholinephosphotransferase
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2-aminoethylphosphonate + acetyl-CoA <=> 2-Acetamidoethylphosphonate + CoA + H+ 2.3.1.280 (aminoalkyl)phosphonate N-acetyltransferase
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(hydroxyphosphinyl)pyruvate + acetyl-CoA + H2O <=> H+ + 2-(hydroxyphosphonoylmethyl)malate + CoA 2.3.3.18 2-phosphinomethylmalate synthase
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phosphonoacetaldehyde <=> Rhizocticin_D not assigned
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S-adenosyl-L-methionine + alpha-D-ribose_1-methylphosphonate_5-phosphate + reduced_acceptor <=> 5-phospho-alpha-D-ribose_1,2-cyclic_phosphate + methane + 5''-deoxyadenosine + L-methionine + H+ + acceptor 4.7.1.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase
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H+ + Phosphonopyruvate <=> phosphonoacetaldehyde + CO2 4.1.1.82 phosphonopyruvate decarboxylase
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hydroxymethylphosphonate <=> Formylphosphonate not assigned
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(R)-2-(phosphonomethyl)malate <=> 2-Oxophosphonobutanoate not assigned
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